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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e76cc10e0b8cc750c89091a68af86b47e7d7266e69e81b0ad601c5eefe2c248' 
  AND token = 'BjIiGeN2hFFSDxL3HJWOO7/HfdegkywTH4LutfyD9Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}