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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5bd970263e08446582235d48de81b959e88e2915a644aa2da5cdffb1a2c2c8b8' 
  AND token = '0x2wpfzFLiizfoVqM+Nse3RKiID2OtIrCO8PpI54RYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}