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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ea8b19c958f72977833c5c651103afbf9216afb146ffa83e5365392f33875745' 
  AND token = 'RIUhcb1ZM/gWm+dljqUa965R+F2xLs05iYBycE99jPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}