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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e0e55596dd89dbaa25e9f00278531f17ab89ac5c9b4274a90de0f4fb6e85da81' 
  AND token = '+9CVCzdZx0qWya2eYL/OnfkuXgr19r0fQYmDdBs4nJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}