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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22dededfe33e774fd28ef2230fa6f19a20834b900f1b099d006e7a2c2d2418fd' 
  AND token = 'MRLl5eT8NoaEfrcFYy8u6HdnOQqy6DoykfWkylETsa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}