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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '644f364ae43f67444371da4028bb809540bd3c86cbcd3cc9752b965b0472576f' 
  AND token = '0Epl9/68wQs4pY12dfR76leuVR3P5DO5gDxmHuVX5Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}