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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7c8e956456ec8ff5a731b841aaa8a3ef4fccb49b0469b691174a72a1249dde33' 
  AND token = 'yOZnKujWk72L7Vrg135ocY5G021dmNDePoNTlOAhNmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}