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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'af7f9d5a2cc0d307d541486a098b9d3728c8facad694b22de5e781c9a1df0a40' 
  AND token = 'Gz0cQDZdKxlDZC34tslSjVrr2+XDbBH/aNo840De+bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}