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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10017ef302f02470468f9b4ae09a9524c7979fdd41ab41e1078ccaa63a6c4b39' 
  AND token = '1DnL+vZFeUq2xYkVsx9F7hHkUciLB/7ErtjvrSUvfcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}