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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '725534b21b861837632d12aa3d966e6a40c687263bc85d6ba1f7ad4201a221dd' 
  AND token = 'gYbQNR0uiu2OuvS0WPqugMtPoVcf/xWFgbtvgYyywNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}