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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9c52e16b83ba1a53855aa3de218fb4121d9ea7736a6076d3c58e64560f330761' 
  AND token = 'YaR51lGFJTO5/fMFrxRE8Rx2njPM0UtaJVyFVoxtGKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}