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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22e1dcc58b08523808253b69ff309b102678dedf154f2a3ab637c37b0cba1e77' 
  AND token = 'tLs5EZ8Asr6QqK2wne7BPMxXftvM68jRl6X4RAdyqWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}