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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2553bd1d1d99ab7f163e3cbba5b393e97a61b188ba2378e17034723776e835eb' 
  AND token = 'EHqpRNzMrymzc6YocIzuZVQkKn9lDFF03Jytf36XzmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}