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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5c06d6b8fa8502ccc22be49e4f109307c67afd67d7c014a89fca4f6e6c6377e5' 
  AND token = '6aV0Y2RdsQX5s+pKE800nUQw9C2lXW3EAjrtiAXtrzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}