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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49b9d9af0d35c85972ccaf4d9c10f786a2172a013c3e54a227706bbc84c67a19' 
  AND token = 'LBkOUvQQVVjxue5TUIygadGEpT778Zj56SDoO6T8kx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}