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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5a22eaa19658923d0c681c596fa7b15e0e38cd76c0eeb9f0700be7a3c1158525' 
  AND token = 'LNn4Lt9kCC1zBr+hVo43r7mBb12/TcyE1Lc6lgpcz4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}