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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9c49f15deafab1686694f2f6f1a12b8eb3fa1a06ff6703a526bec78348b92e53' 
  AND token = 'M3wv8NHd+dLBUbUJ85M/DtYoDg+Edb8N31cAfHBht2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}