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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5005d901170a1638e89c47ede65d51da1a16547809c2e317317f9e28868fe2ab' 
  AND token = 'narteio6YOpn23J6kH/potsubhCP6whLNmCJrNGksWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}