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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c0bc408c584219aab4c31ab09c044bfdd0574830222b0ee3a7f70d2be226cd57' 
  AND token = '52ulcOQdnZlD1TsdbiWSoMxGlTw4jxRGMC0Dk8uQJb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}