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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e57f8c7a75d5f7a2f41740cc5e85e55efb78af26b1549a4f61a3a945a8a5e18d' 
  AND token = 'NP04sZo5drp7BYEEdKOzRLMD9Rxq7goYljvdMBMDB5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}