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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'af65e4e6866124a2e72960227969ff6f908031001e5f945de52319a8a0baa8d6' 
  AND token = 'RVlgqJWrB3xyIh1QVXt6SPaN7L69dqd6cu/Vgkhx4+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}