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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b449704044626dfa9a81230f4a6b8b0dbbbb1f525c8001d062efe28582f0b708' 
  AND token = 'MumhfdmQnrUWT1faUuE/SwUZ/SPQEIBAHtnFOwVveiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}