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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49efd6681555467dce1e41ea50cdc53a3ac33b05d67451de6bcbefece200538e' 
  AND token = 'Y3RY2yP8qKuWpjCP7kqH2s6B+PKQN6iWBHx+44Tfuvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}