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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6d2b3a318e3a3417c0affc678474b0ed88fdff1549103bfa7f7fbbbce541e72b' 
  AND token = 'LmmCDhU2sBEAkaRVPI6yWwqzkh2ykxCOgCQoXSwXsQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}