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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2ce94791b90e4a5be8c9a12c204991c4b4edae77607733361ded50a730f0369' 
  AND token = 'SpdQV6JcwqARxZsBQeV9K4mRzDNX4B+OwnQ4V5EmD2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}