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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cde3783cbd1d171e7b90e90a66e4a85d8aa87efbcaf9c3699abfb5c940835349' 
  AND token = 'EuSxyWU341+zpJv2+5AMR+0UfNh6R+XtHQr8LXM6nPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}