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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e9376109142a75ab4d60a20dc331cd562cfba8d42f7ddea00bbd09ce81376c1b' 
  AND token = 'NLHSaT9w0iI5+bKNaMggTCkuhllY58eQTRqS0E0VxeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}