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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cce927f51600e24eb12966c70cfc0140a244de455d273e46293336dbc7c37e40' 
  AND token = 'z/wSK1jjKrKK6pUhzK2FNJVabuK9yFk9cmsafThjSuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}