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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f7e9f6236b7146da4200664870c901e75e5a50f6238ab2d1a39c630fc5659292' 
  AND token = '9akZyOSvUIOzgaRGCZbnYcMdchdfwvzzcFfZvtO+evI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}