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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fbe35eb401dc5e9c1fbfd83e726e692eb4b604a0bd377de9d1355c28960d8519' 
  AND token = 'PDRFmYNCSnNEkEyytE81MHjvj+U9UpIQKEhayDXahjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}