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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f15e643df0247066af4c88da56f7eea6102ae362ac064e9aa125cab6a5c26bbe' 
  AND token = 'xVWD3lek/gB/AYmHfxiSksPgZOyy+qa/HRmAS2pdZWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}