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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3f85afde0f7a131d99db0c1d22f798b74fe9c35190ca49583632d1994268e589' 
  AND token = 'CcJhk9BvyL99Y00Pwr9fzArAZi1076wsZYD6N4eQn5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}