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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '69c21227aadd131518e38e056683b083247d78b18b33012d321a8a9ee0a1e284' 
  AND token = 'kmEA3sXg8aKEXJ8aPG+rLk9LOAXby1xalbmULMXXVYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}