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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0d0374e3325e77629faf65726fe60eb518b91d68a6202fb394173e95378ac3e8' 
  AND token = '8TIQInvngJDTiY2YKH1/SHEegjCikf2FbiUvTlcFbpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}