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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2142e6f67c38625d3a3face57299c1f0a33f05f9f64df95f2416d5410bf006af' 
  AND token = '2afvruddYMSXa7RITXLOV+WFzlZdmdEIyHhyHzQAI0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}