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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59907c64faeb5aa6b265aace163599bb1e20442f7f8b1da532a9c3a03c566ad0' 
  AND token = 'nOtxyE+6WSRcOXLFMOFdkwyK0HAk5taLK42OoXVw28I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}