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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ad3555f984c70e9fa27dde753f305d8e197b43501e0bbdd18ccefc35d014971c' 
  AND token = '0N09AgEMXA7syRQnkSYcgEcM249e96WbQC7gCe6vvPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}