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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '714e3f44d20b80ede90f71d6778e253834685b6f7587982a4a9d9740fccaed54' 
  AND token = 'FA4rinFNCoFRnAWPEmFMtYusT/H/kMEe6pD0a/7Bhrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}