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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '33677ce520213d7767add9601f5ea80489b9ec3b328ae49d3e70d7102d062c45' 
  AND token = 'Qj+grnR3WKY0CP2wStWeOz5zvlPSUNHKL3LoYlltdRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}