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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ee1049216f61d6b74f8f22670ebce5deee9d3d0a057269e72f4ad34cf15ee65' 
  AND token = '+rSetc8y5+Wb/2OA/JZ/eHTl+MBsDyCUGYMLunatZfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}