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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0e445389edbb4e4d98fe2b49471ec499ff1087a4af8c75e707707689d44cb19b' 
  AND token = 'FsLxprDcpxMjbLZaPOMTesv+L1s7/BY7r3DD3pfODrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}