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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f508544b846a234483d68fb366626501e27c9e13f7a08c9d88273be35efe67a2' 
  AND token = '2z77BmMoP2EOIW6lsUssmXYBn32azwoB7jZGYz7BaHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}