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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '157c6b43ac3d6473927ee404280e22f3a7f124d45a10accf0ef753baec7343a3' 
  AND token = 'l8QVUW0C0ozJqTxOgHt3/9Ii3uCrswT4fiEtFhLTE08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}