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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b559acd33b33e6db69c4646f054b679e629de0307bb5e1e50e6ac7dca741d735' 
  AND token = 'yP1v78Y+mvxDRbVuhRdLx0D3KUDvnCzdFOWuDh+klgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}