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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed21c4ff630af3411387c4e43df6354e168e27844558a49e7b40c094ffc76a65' 
  AND token = 'UrddmBA59orfbZu0u03eGe8G1I9hZMvO89e0wnMex9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}