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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd8f035a70f19e9b37e3a76a91ffe09a0c15059e070d07df1e4ad060284f07c11' 
  AND token = 'HFTTChpm4tuwHnUZk1IwbSnUWFff8grAfh6guGFG9co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}