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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd53d3aabb97af2ad89d1c21149a016f34e8b1bc8b69e1e308c0858b87982f957' 
  AND token = 'nJdCPWrlrINpCbRd8cOnHcdajWRwPI4ozeNYT8S6GcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}