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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a2c50f7358a103934fd9bf42595e3fa990ed3a670977cd279342f70f3c37a7f7' 
  AND token = '8ity7ZD/kWXQecTmP+rw+ODz8rwgBzQ1VR8jOTRaNX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}