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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f8339f780e50dc4e86b6f5390403a307796e6d6d16259d107e9213e5b55acb3' 
  AND token = 'Wuf2HNipIEsDe1t4Y+m1FYR0rQjIg2CDNiHWuN8weSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}