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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '552013314f41758a08fd3cfc9dd288d8f3642a5b15d420967306823bd4f13a57' 
  AND token = '2R6QCX9181r+1Q4iMyw/wW9OYTh+hiFS1cKibkqk5C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}